MicroRNAs (miRNAs) are small (approximately 22nt) ribonucleotides found in animal and plant cells which play important roles in cell differentiation, tissue development and apoptosis by regulating gene expression and protein translation. Altered expression of microRNAs has also been seen in numerous mammalian cancers. CapitalBio has developed two microRNA arrays, the mammalian miRNA array (human, rat, mouse) and the plant miRNA array which contain 1320 and 426 non-redundant microRNA probes, respectively.
Affymetrix 新近推出的人类转录组和剪接体分析芯片(Human Transcriptome and Splice Junction Array)，又称GG-H芯片(Glue Grant Human Transcriptome Array，GG-H)，是Affymetrix与联合Stanford大学和NIH的Glue Grant项目，共同合作研发的一种基于全新设计理念设计的芯片。这种芯片针对人类转录组全方位检测的需要，分别对外显子和外显子连接区设计探针，可同时用于基因表达、替代性剪接和编码区SNPs检测；另外，该芯片还收录了大量非编码RNA片段，可用于非编码RNA转录的检测。该芯片通过高效扩增方法，可以从低至50ng的总RNA起始进行高通量、低成本检测，非常适合临床样本转录组水平全面基因组研究。
CapitalBio Expression Profiling Array Services guarantee the quality of your results. The exceptional quality of our services was highlighted in the U.S. FDA-sponsored MicroArray Quality Control (MAQC) project (Nature Biotechnology, 24(9): 1140-1150, 2006). CapitalBio’s highly trained specialists manufacture, hybridize, scan, and conduct a preliminary analysis of your arrays. There is no need for you to train your lab personnel in highly specialized techniques or purchase expensive instruments to fabricate arrays in-house. Moreover, because CapitalBio products range includes ready-to-use arrays to customizable array designs, which enables you to explore the complex bio-world and answer your research questions more quickly.
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